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Although I am not a vet and would definitely not recommend your following my advice without consultation with your own vet, I will tell you how I would attempt to handle a similar situation with my own horse. Since many of these organisms thrive in damp situations, I would be inclined to clip my horse's legs to prevent the hair from holding moisture against the legs. I would also be careful to keep the legs as dry as possible, including not allowing the horse outside until the dew had burned off the grass in the morning. However, I would definitely put the horse out to pasture on sunny days. The sun has a significant healing effect on many skin infections (unless, of course, the horse is photosensitive). I would avoid washing the legs as much as possible (again, not wanting to dampen the skin unless absolutely necessary) but would probably try different medications to try to kill the infective organism. If the organism proved fungal, I would use a fungicidal product (some of the human athlete's foot medications are occasionally used for this purpose). If the infective organism was determined to be bacterial, I would use a topical antibiotic medication.
I would not bandage the legs, though I would take reasonable precautions to prevent injury or irritation to the skin on the legs. Infective organisms are opportunistic and will more quickly invade thin, broken, or irritated skin. Skin which is subjected to insect bites may also be made more susceptible to infection. Young animals, those who are poorly nourished, and those who are kept in poorly ventilated, damp, sunless environments are also particularly susceptible.
I wish you luck in combating this skin condition. It's going to be very difficult to overcome unless you can effectively disinfect your mare's living environment, but sunnier and drier days will definitely help.
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